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David Kailin's avatar

Really superb article! How can one obtain pyridoxamine in the US (in 2024)? The FDA appears to have recategorized it as a drug. Are there reliable (and affordable) bulk powder suppliers outside the US?

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Olafur Pall Olafsson's avatar

Thanks. I'm not sure how to obtain it in the US. It looks like there was some petitioning to revoke its classification as a drug to allow it to be sold as a supplement. That doesn't seem to have been successful yet.

https://www.thefdalawblog.com/2017/11/citizen-petition-to-declare-pyridoxamine-not-excluded-from-the-dietary-supplement-definition/

https://www.nutraingredients-usa.com/Article/2018/03/19/CRN-supports-making-pyridoxamine-a-legal-dietary-ingredient-again-cites-precedent-potential

I don't recall seeing pyridoxamine for sale anywhere in the US but it is available in Europe from this vendor:

https://www.supersmart.com/en/shop/strengthening-organism/pyridoxamine-supplement-0443

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David Kailin's avatar

Thank you for pointing out that European vendor! Their product also contains acacia gum, which I cannot metabolize and hence is toxic for me. Their product is also pretty spendy for a humble B vitamin. There are a few Chinese and Indian vendors to consider.

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Olafur Pall Olafsson's avatar

It's unfortunate that you can't metabolize acacia gum, and yes, their product is very pricey for a B vitamin. I don't know how reliable the Chinese and Indian vendors are. I haven't looked into that.

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